中文名稱(chēng):N,N'-二乙酰-L-胱氨酸
CAS號(hào):5545-17-5
中文別名:N,N'-二乙酰-L-胱氨酸 ,N'-二乙酰-L-胱氨酸;N,N'-二乙?;?L-胱氨酸;乙酰半胱氨酸EP雜質(zhì)C;雙乙?;?L-胱氨酸;S-[2-(乙酰氨基Chemicalbook)乙基]羧酸;N,N'-二乙酰-L-胱氨酸;乙酰半胱氨酸雜質(zhì)C(EP);乙酰半胱氨酸相關(guān)化合物C(USP);乙酰半胱氨酸雜質(zhì)10
英文名稱(chēng):L-Cystine,N,N'-diacetyl-
分子式:C10H16N2O6S2
分子量:324.37
顏色:White to Light Beige
生物活性:N,N'-diacetyl-L-cystine(DiNAC)是一種具有免疫調(diào)節(jié)特性的N-乙?;腚装彼岬亩蚨垠w。N,N'-diacetyl-L-cystine是嚙齒類(lèi)動(dòng)物中接觸敏感/遲發(fā)型超敏反應(yīng)的有效口服活性調(diào)節(jié)劑。N,N'-diacetyl-L-cystine在高脂血癥兔(WHHL)中也具有抗動(dòng)脈粥樣硬化的作用。
靶點(diǎn):Immunomodulator
體內(nèi)研究:N,N'-Diacetyl-L-cystine(DiNAC;0-973.11μg/kg;oraladministration;daily;for12weeks;WHHLrabbits)treatmentreducesby50%tChemicalbookhoracicaortaatherosclerosis,withoutaffectingplasmalipidlevels.AnimalModel:Maleheritablehyperlipidemicrabbit(WHHL)rabbits(10-22weeks)Dosage:0μg/kg,9.73μg/kg,or973.11μg/kgAdministration:Oraladministration;daily;for12weeksResult:Reducedby50%thoracicaortaatherosclerosis,withoutaffectingplasmalipidlevels.